Is an Apo A and B test the same as a cholesterol test?
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Is an Apo A and B test the same as a cholesterol test?

Last updated: 20 April 2026

An apolipoprotein test, often called an Apo A and Apo B test, measures the proteins found on the particles that carry cholesterol in your blood. These proteins help move cholesterol around your body. The test relates to heart health but it is not the same as a standard cholesterol test.

A cholesterol test measures how much cholesterol and triglyceride is in your blood. Instead, an Apo blood test measures specific proteins that sit on the surface of lipoprotein particles, which transport cholesterol and other lipids in the blood. This can give a clearer idea of how many of these particles are present and can help assess your risk of heart disease.

Below, we explain what an Apo A and Apo B test involves, how it differs from a cholesterol test and how both tests can help you understand your heart health.

What is an Apo A and Apo B test?

An Apo A and Apo B test is a simple blood test that checks two proteins linked with cholesterol transport. These proteins sit on the surface of lipoproteins, which carry cholesterol through your bloodstream.

Apo A1 is mainly found on HDL cholesterol. HDL is sometimes referred to as “good cholesterol”, the type that helps remove excess cholesterol from the arteries. Higher Apo A1 levels tend to be linked with a lower risk of developing heart disease.

Apo B is mainly found on LDL cholesterol, commonly known as “bad cholesterol”. LDL carries cholesterol to the tissues and can contribute to a build up of plaque in the arteries over time. Higher Apo B levels may be linked with a higher risk of cardiovascular disease.

Looking at both Apo A1 and Apo B provides a clearer picture of the balance between cholesterol particles that help protect the heart and those that may increase risk. At Bluecrest Wellness, the Apo Blood Test measures both Apo A1 and Apo B levels to help you understand your heart health.

What are apolipoproteins?

Apolipoproteins are proteins that help your body transport and process fats. Each type plays a specific role. Apo A1 helps clear cholesterol from the blood. Apo B helps carry cholesterol to cells. Changes in these protein levels can give useful insights into how well your body is managing cholesterol.

How is an Apo test different from a cholesterol test?

A cholesterol test, sometimes known as a lipid panel, measures the amount of cholesterol and triglycerides circulating in your blood. It usually reports:

  • Total cholesterol

  • LDL cholesterol

  • HDL cholesterol

  • Triglycerides

These results help build an overview of your cholesterol levels and your possible risk of developing cardiovascular problems. Book a cholesterol test to get a full overview of your cholesterol levels.

An Apo A and Apo B test does not measure the amount of cholesterol. It measures the proteins on the particles that move cholesterol around. This can help estimate how many cholesterol carrying particles are in your blood, which can be useful for understanding cardiovascular risk.

Some people may have cholesterol levels within a normal range but still have a high number of cholesterol carrying particles. Checking Apo B levels can help identify this.

Both tests contribute useful information about heart health and are often used together to give a fuller picture.

How do Apo A and Apo B relate to cardiovascular risk?

Apo A1 is linked with HDL cholesterol. Higher levels are usually seen as helpful as HDL particles assist in clearing cholesterol from the bloodstream.

Apo B is linked with LDL and other particles that can contribute to atherosclerosis, the gradual narrowing of the arteries. Higher Apo B levels may indicate more LDL particles and therefore a higher chance of developing cardiovascular disease.

Healthcare professionals sometimes review the ratio of Apo B to Apo A1. A higher ratio can suggest a greater imbalance between harmful and protective cholesterol particles. This can be a useful marker in people who have other risk factors such as diabetes, high blood pressure or a family history of heart disease.

Why might I be advised to have an Apo A and Apo B test?

An Apo test may be useful if you want more detailed information about your cardiovascular risk. It can be helpful if your cholesterol results do not give the full picture or if you want a closer look at your heart health.

Situations where an Apo test may be useful include:

  • Your cholesterol results are borderline

  • You have a strong family history of early heart disease

  • You have diabetes or metabolic syndrome

  • You have already been diagnosed with cardiovascular disease

  • You want to monitor how lifestyle changes or treatment are affecting your heart health

An Apo test can also provide reassurance for anyone wanting a clearer understanding of their heart health.

What do high Apo A or Apo B levels mean?

High Apo B levels can indicate that you have more LDL or similar particles in your blood, which could increase the chance of plaque building up in your arteries. Making lifestyle changes, such as improving your diet, exercising more or managing your weight, can help reduce this risk.

Low Apo A1 levels mean there may be fewer HDL particles available to help clear cholesterol from your bloodstream. This can also affect your cardiovascular health.

Your results should be considered alongside other factors such as age, blood pressure, cholesterol levels and lifestyle habits. One result on its own does not diagnose heart disease but can provide useful information about your overall heart health.

What does an Apo test involve?

An Apo A and Apo B test involves a small blood sample taken from a vein in your arm. The procedure only takes a few minutes and most people feel very little discomfort.

Once your sample has been analysed, you will receive clear results outlining your Apo A1 and Apo B levels. These can be discussed with a healthcare professional to understand what they mean for your heart health.

Should I have a cholesterol test or an Apo test?

A standard cholesterol test is usually the starting point for checking cardiovascular risk. It provides a broad overview of your cholesterol levels and is suitable for most people.

An Apo blood test can be useful if you want a more detailed look at the number of cholesterol carrying particles in your blood. It may be particularly helpful if you have existing risk factors or if your cholesterol results do not fully explain your risk profile. Find out more about the Apo Blood Test

Both tests play a part in understanding long term heart health. The right choice depends on your personal circumstances and what level of detail you want.

Check your cardiovascular health

A cholesterol test can provide clear insights into your cholesterol levels and your potential cardiovascular risk. At Bluecrest Wellness, we offer a comprehensive cholesterol test that measures HDL, LDL, total cholesterol and triglycerides to help you understand your overall heart health.

You can also choose a full body health check, which looks beyond cholesterol alone to assess a wider range of health markers. This broader approach can help identify early signs of potential health issues and provide a more complete picture of your wellbeing.

All our tests are available throughout the UK, making it easy to find a location near you. We work closely with leading UK laboratories and provide fast, accurate results.

BOOK NOW

Need help? Call free on 0800 652 2183 to speak to one of our team.

AUTHOR

Anna Jones

Chief Nursing Officer, Bluecrest
As the Chief Nursing Officer at Bluecrest, Anna is committed to driving high quality care and services and ensuring excellent clinical governance and accuracy alongside developing new innovative testing to supporting preventative health. | LinkedIn
REVIEWED BY

Graham Jones

Medical Writer
As a Medical Writer for Bluecrest, Graham has a passion for science communication and is dedicated to making health information clear, accurate, and accessible, turning complex medical information into content that empowers people to take charge of their health and supports preventative care.
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