Do Men Have Progesterone?
ArticlesMale Health

Do Men Have Progesterone?

Last updated: 8 July 2026

Progesterone is often thought of as a “female hormone” because of its well-known role in the menstrual cycle and pregnancy. But men also produce progesterone and it plays a far more important part in male health than many people realise.

From supporting testosterone production to helping regulate mood, sleep and overall hormonal balance, progesterone has its own behind-the-scenes job in the male body. When levels are too low or too high, it can contribute to symptoms that may be easy to overlook or mistake for something else.

Here’s what progesterone does in men, the signs it may be out of balance and when it might be worth checking your hormone levels.

What is progesterone?

Progesterone is a steroid hormone made mainly in the adrenal glands in men, with smaller amounts produced in the testes. While it doesn’t play the same reproductive role it does in women, progesterone is still essential for several core processes in the male body.

It acts as a precursor hormone, meaning the body uses it to produce other important hormones, including testosterone and cortisol. For this reason, healthy progesterone levels help keep the wider hormone system in balance.

What does progesterone do in men?

Men don’t need high levels of progesterone, but they do need enough of it for key functions. In men, progesterone helps support:

Testosterone production Progesterone is one of the building blocks the body uses to create testosterone. If progesterone levels are very low, testosterone production may be affected.

Sperm development Healthy sperm formation relies on a stable hormonal environment. Progesterone plays a supporting role in spermatogenesis.

Mood and brain function Progesterone interacts with receptors in the brain that influence calmness, sleep quality and emotional regulation. Imbalances may contribute to irritability, anxiety or difficulty sleeping.

Prostate health Some studies suggest progesterone may help counteract the effects of excess oestrogen in men and support overall prostate function.

Balancing other hormones Because progesterone is part of the same hormonal pathway as cortisol, DHEA and testosterone, the right levels help keep the whole system working smoothly.

Signs of low progesterone in men

Low progesterone isn’t always easy to spot on its own, but because it affects testosterone and other hormones, symptoms often overlap.

Common signs may include:

  • Reduced sex drive
  • Erectile difficulties
  • Low mood or irritability
  • Poor sleep or restless nights
  • Fatigue that doesn’t improve with rest
  • Reduced muscle strength
  • Fertility challenges
  • Unexplained weight changes

Because these symptoms can be caused by several different hormonal changes, the most accurate way to know what’s going on is through a blood test.

Signs of high progesterone in men

High progesterone is less common, but it can happen, often due to medication, stress or underlying health conditions.

Symptoms may include:

  • Low libido
  • Mood swings or increased anxiety
  • Breast tenderness
  • Erectile dysfunction
  • Changes in body hair
  • Fatigue or low energy

In some cases, high progesterone can also indicate adrenal issues or problems within the hormone production pathway.

What causes progesterone imbalance in men?

Several factors can influence progesterone levels, including:

Age - Progesterone naturally declines with age, often mirroring the gradual decrease in testosterone.

Chronic stress - Long term stress increases demand for cortisol, which can affect how the body uses progesterone.

Medications - Certain drugs, such as corticosteroids or anabolic steroids, may impact progesterone levels.

Health conditions - Issues affecting the adrenal glands or testes can alter progesterone production.

Lifestyle factors - Poor sleep, high alcohol intake and lack of exercise can all influence hormone balance over time.

How do you check progesterone levels?

The most reliable way to understand your progesterone levels, along with testosterone, oestrogen, thyroid markers and other key hormones, is a simple blood test.

A comprehensive hormone panel can help you understand:

  • Whether progesterone is low, high or within the expected range
  • How it relates to testosterone and other hormones
  • Whether symptoms may be linked to a broader hormonal imbalance
  • What next steps might be helpful

The Advanced Male Hormone Profile is a practical way to get a clear understanding, combining a detailed blood test with a private GP consultation to talk through the results.

When should men consider a hormone profile?

If you’ve noticed changes in your energy, mood or overall wellbeing, it may be worth checking your hormone levels to get a clear picture.

You might consider testing if you’re experiencing:

  • Ongoing low libido or changes in sexual function
  • Fatigue that doesn’t improve with rest
  • Difficulty sleeping
  • Mood changes or irritability
  • Reduced muscle strength or slower recovery
  • Fertility concerns
  • Unexplained weight gain or loss

Understanding your hormone levels gives you a foundation to make informed decisions about next steps.

Check your hormone levels with the Advanced Male Hormone Profile

If you’re experiencing symptoms or simply want to check in on your hormone health, the Advanced Male Hormone Profile offers a clear and convenient way to get answers. It tests key hormones including progesterone, testosterone, thyroid hormones and more.

You’ll receive:

  • A quick and convenient blood test
  • A detailed, easy to understand report
  • A private 15 minute GP consultation to discuss your results

Whether you’re looking for answers or want to take proactive steps with your wellbeing, this profile can give you valuable insight into what’s happening behind the scenes.

BOOK AN ADVANCED MALE HORMONE CHECK TODAY

Need help? You can reach out to our corporate team on 0808 168 9219

AUTHOR

Anna Jones

Chief Nursing Officer, Bluecrest
As the Chief Nursing Officer at Bluecrest, Anna is committed to driving high quality care and services and ensuring excellent clinical governance and accuracy alongside developing new innovative testing to supporting preventative health. | LinkedIn
REVIEWED BY

Dr Martin Thornton

Chief Medical Officer, Bluecrest
As the Chief Medical Officer at Bluecrest, Dr Thornton is dedicated to improving health outcomes through patient-centered prevention strategies and in identifying what can be measured and tracked to improve health. | LinkedIn
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